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Agenus Earns $20M BMS Milestone in Antibody Alliance

Doses the first patient in Phase I trial of AGEN1777, an Fc-enhanced bispecific anti-TIGIT antibody in cancer.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Agenus Inc., an immuno-oncology company with a pipeline of checkpoint antibodies, cell therapies, adjuvants, and vaccines, has triggered the first development milestone payment under its global licensing agreement with Bristol Myers Squibb for AGEN1777, an Fc-enhanced bispecific anti-TIGIT antibody. Agenus will receive a $20 million payment with the dosing of the first patient.   This Phase 1 dose escalation study is designed to evaluate the safety, tolerability, and preliminary clinical activ...

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